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Found 210 Enz. Inhib. hit(s) with Target = 'Glutaminyl-peptide cyclotransferase-like protein'
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190690(US9181233, 67)
Affinity DataKi:  10nM ΔG°:  -46.4kJ/mole IC50:  80nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM124974(US8772508, 8)
Affinity DataKi:  11nM IC50:  580nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299866(CHEMBL578153 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...)
Affinity DataKi:  34nM IC50:  430nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190685(US9181233, 60)
Affinity DataKi:  40nM ΔG°:  -42.9kJ/mole IC50:  450nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299867(CHEMBL565907 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...)
Affinity DataKi:  41nM IC50:  230nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190679(US9181233, 52)
Affinity DataKi:  50nM ΔG°:  -42.4kJ/mole IC50:  680nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299865(CHEMBL567406 | N-(-1-(3-(5-Methyl-1H-imidazol-1-yl...)
Affinity DataKi:  51nM IC50:  320nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM124971(US8772508, 2)
Affinity DataKi:  55nM IC50:  530nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190676(US9181233, 47)
Affinity DataKi:  60nM ΔG°:  -41.9kJ/mole IC50:  400nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190680(US9181233, 54)
Affinity DataKi:  60nM ΔG°:  -41.9kJ/mole IC50:  590nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM124975(US8772508, 9)
Affinity DataKi:  67nM IC50:  340nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299868(CHEMBL565908 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...)
Affinity DataKi:  67nM IC50:  460nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM124973(US8772508, 4)
Affinity DataKi:  76nM IC50:  730nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190695(US9181233, 86)
Affinity DataKi:  80nM ΔG°:  -41.2kJ/mole IC50:  290nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM50299864(CHEMBL574357 | N-(1-(3-(5-Methyl-1H-imidazol-1-yl)...)
Affinity DataKi:  80nM IC50:  340nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190687(US9181233, 62)
Affinity DataKi:  80nM ΔG°:  -41.2kJ/mole IC50:  480nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190671(US9181233, 10)
Affinity DataKi:  80nM ΔG°:  -41.2kJ/mole IC50:  480nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190681(US9181233, 55)
Affinity DataKi:  80nM ΔG°:  -41.2kJ/mole IC50:  490nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190678(US9181233, 50)
Affinity DataKi:  80nM ΔG°:  -41.2kJ/mole IC50:  760nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190677(US9181233, 49)
Affinity DataKi:  90nM ΔG°:  -40.9kJ/mole IC50:  360nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM124972(US8772508, 3)
Affinity DataKi:  96nM IC50:  620nMpH: 8.0Assay Description:All measurements were performed with a BioAssay Reader HTS-7000Plus for microplates (Perkin Elmer) at 30C. QC activity was evaluated fluorometrically...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190688(US9181233, 63)
Affinity DataKi:  100nM ΔG°:  -40.6kJ/mole IC50:  220nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190694(US9181233, 85)
Affinity DataKi:  100nM ΔG°:  -40.6kJ/mole IC50:  470nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190669(US9181233, 8)
Affinity DataKi:  110nM ΔG°:  -40.4kJ/mole IC50:  640nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190672(US9181233, 22)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/mole IC50:  520nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190689(US9181233, 65)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/mole IC50:  530nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190696(US9181233, 87)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/mole IC50:  550nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190684(US9181233, 59)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/mole IC50:  560nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190693(US9181233, 84)
Affinity DataKi:  120nM ΔG°:  -40.2kJ/mole IC50:  570nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190674(US9181233, 39)
Affinity DataKi:  130nM ΔG°:  -40.0kJ/mole IC50:  800nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190682(US9181233, 57)
Affinity DataKi:  130nM ΔG°:  -40.0kJ/mole IC50:  830nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190692(US9181233, 83)
Affinity DataKi:  140nM ΔG°:  -39.8kJ/mole IC50:  570nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190683(US9181233, 58)
Affinity DataKi:  140nM ΔG°:  -39.8kJ/mole IC50:  720nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190691(US9181233, 68)
Affinity DataKi:  150nM ΔG°:  -39.6kJ/mole IC50:  410nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190686(US9181233, 61)
Affinity DataKi:  170nM ΔG°:  -39.3kJ/mole IC50:  760nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190675(US9181233, 46)
Affinity DataKi:  180nM ΔG°:  -39.1kJ/mole IC50:  640nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190670(US9181233, 9)
Affinity DataKi:  200nM ΔG°:  -38.9kJ/mole IC50:  760nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM190673(US9181233, 24)
Affinity DataKi:  230nM ΔG°:  -38.5kJ/mole IC50:  850nMT: 2°CAssay Description:This novel assay was used to determine the kinetic parameters for most of the QC substrates. QC activity was analyzed spectrophotometrically using a ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652300(US20240059675, Example 4)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652305(US20240059675, Example 8)
Affinity DataIC50: <1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652310(US20240059675, Example 13)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652312(US20240059675, Example 15)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652313(US20240059675, Example 16)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652318(US20240059675, Example 21)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652324(US20240059675, Example 26)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652363(US20240059675, Example 32)
Affinity DataIC50:  1nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652297(US20240059675, Example 1)
Affinity DataIC50:  2nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652298(US20240059675, Example 2)
Affinity DataIC50:  2nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652299(US20240059675, Example 3)
Affinity DataIC50:  2nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetGlutaminyl-peptide cyclotransferase-like protein(Homo sapiens (Human))
Probiodrug

US Patent
LigandPNGBDBM652301(US20240059675, Example 5)
Affinity DataIC50:  2nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
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